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Cornell University

Cornell Center for Materials Research

Cryo Transmission Electron Microscopy (TEM)

The CCMR's suite of cryoTEM-focused instruments includes the Arctica and F200, and available time at the Rutgers Krios in Piscataway, NJ.  The Arctica has STEM capabilities but is primarily operated in TEM mode. Each instrument has its own strengths. The Arctica and Krios are primarily geared towards collecting high-throughput, high-resolution imaging for single particle  cryoEM, and the F200 is an easy-to-use general purpose TEM.  More specifics can be found on the individual instrument pages.  Users that are interested in TEM or STEM in the CCMR are encouraged to contact any of our knowledgeable facility managers to discuss experimental needs; we will be happy to guide you through the process.  

The Gallery below shows some images and data that were taken on some of these instruments.  Please see the individual instrument pages for more specifics on instrument capabilities and data that can be acquired from our world class microscopes.

Chains of Cry1: CryoEM micrograph of mutant Arabidopsis.thaliana(plant) Cryptochrome1(AtCry1) overlaid with representative 2D classes of tetramers, dimer of tetramers and trimers of tetramers. This mutant pushes the normally tetrameric AtCry1 into filamentous chains which disrupt the organisms ability to respond to blue-light early in development. || Submitted by: Dhruva Ajit Nair || Advisor: Brian Crane || Data like this can be acquired on our Arctica or F200 microscopes.

Chains of Cry1: CryoEM micrograph of mutant Arabidopsis.thaliana(plant) Cryptochrome1(AtCry1) overlaid with representative 2D classes of tetramers, dimer of tetramers and trimers of tetramers. This mutant pushes the normally tetrameric AtCry1 into filamentous chains which disrupt the organisms ability to respond to blue-light early in development. || Submitted by: Dhruva Ajit Nair || Advisor: Brian Crane

Binary Tiles at the Quantum Scale: Core-shell super crystal/super-molecular quantum dot tile assemblies made of a binary mixture of PbSe Quantum Dots at 21nm and 7 nm assembled via nanofluid evaporation on a fluid substrate. || Submitted by: Jonathan Palumbo || Advisor: Tobias Hanrath || Data like this can be acquired on our Arctica or F200 microscopes..

Binary Tiles at the Quantum Scale: Core-shell super crystal/super-molecular quantum dot tile assemblies made of a binary mixture of PbSe Quantum Dots at 21nm and 7 nm assembled via nanofluid evaporation on a fluid substrate. || Submitted by: Jonathan Palumbo || Advisor: Tobias Hanrath